SES Flow Type Franz Cells |
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A SES flow type Franz cell is a standard Franz cell
with additional porting for circulating receptor medium continuously
through the receptor compartment of the cell. As with static Franz
cells, flow porting may also be added to the donor compartment if
needed. The phrases "flow thru", "flow cell", and "flow type" are used
interchangeably and refer to flow only through the receptor compartment,
and do not signify anything with respect to the heating jacket. The
first five codes for ordering codes flow thru Franz cells are the same
as for static cells. A sixth code, FT, is added to the end of the first
five codes and the variety of flow porting is followed by donor codes.
Receptor volumes for flow type cells are larger than for the static
cells of the same orifice diameter because the distance between the top
of the heating jacket and the bottom of the joint is greater to
accommodate the arms for the flow work.
Flow thru Franz cells are currently available in four different
varieties and are shown at the bottom of this page.
The word "orifice" as it refers to a Franz Cell is the area of the top
of the receptor chamber that is exposed to the membrane or device
through which transport or permeation is being studied. Standard orifice
diameters are 5mm, 7mm, 9mm, 11.28mm, 15mm, 20mm and 25mm, other
diameters are custom. Corresponding volumes from 5ml to 20ml are
standard and are listed below. There are minimum volumes, especially for
jacketed cells, please find those in the list below as well. We welcome
requests for custom cells! Clamping is achieved through standard o-ring
joints, flat ground (ground o-ring) joints and flat flange joints.
Please note that for most the most popular Franz Cell models we
manufacture our own cell clamps. These clamps are all stainless steel
and are much easier to use than clamps from other suppliers.
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Ordering Information - Part numbers are
generally made up of 2-character codes separated by hyphens.
- 1st code is cell type: 4G is for a jacketed
cell, 6G is for an unjacketed cell
- 2nd code is joint type:
- 00 is an o-ring joint
- 01 is a flat ground (ground o-ring) joint
- 02 is a flat flange joint
- 03 is a spherical joint generally used for corneal work.
- 3rd code is glass type: 00 is for clear
glass, 01 is for amberized glass
- 4th code is orifice diameter in millimeters, 05
through 25
- 5th code is receptor volume in ml, 03
through 20
- 6th code is FT indicating a flow type cell
- 7th code is 01 through 04 indicating
the configuration of the flow ports according to
the variety of flow cell desired. The four present varieties are
pictured below.
- 8th code is optional and indicates:
- VD is for a volatile donor compartment with ground glass
joint and Teflon stopper
- VDFT is for a flow through volatile donor compartment with
ground glass joint and Teflon stopper
- VDOC is for an completely occluded volatile donor
compartment
- VDOF is for flow thru volatile donor compartment without
ground glass joint and Teflon stopper
- 9th code only follows the 8th VD or VDFT
codes if a stoppered donor is required:
- 0725 is for a 7/25 ground glass joint with teflon stopper
- 1420 is for a 14/20 ground glass joint with teflon stopper
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Examples
- #4G-01-00-09-05 is for a 9mm jacketed cell with a flat ground
(ground o-ring) joint and clear glass with a 5ml receptor volume
- #6G-02-01-05-05 is for a 5mm unjacketed cell with a flat flange
joint and amberized glass with a 5ml receptor volume
- #4G-03-00-05-03 is for a 5mm jacketed cell with a spherical
joint and clear glass with a 3ml receptor volume.
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Drawings
- Vertical Stirrer Side View
- Available Joints
- O-Ring Joint Cells
- Flat Ground (Ground O-Ring) Joint Cells
- Flat Flange Joint Cells
- Flat Flange type Franz Cell with flow ports in
receptor
- Flat Ground type Franz Cell with Volatile Flow Type
Donor Compartment
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Photographs &
Information
- V3 3-Station Franz Cell Stirrer
- 6-Station Franz Cell Stirrers
- V9-C Compact 9-Station Franz Cell Stirrer
- V9 9-Station Franz Cell Stirrer
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Typical
Dimensions
These dimensions are for standard Franz cells, the joints variety
does not affect the volume. We can modify most any of these parameters
within the practical limits of blown glass. Do not hesitate to inquire
if your studies need something other than what is listed here. The
term "cell" for sales and pricing purposes includes the two glass
components, the clamp for the joint, and the stirbar.
Standard jacketed cells with clamp and stirbar
- 5mm:5ml volume (4ml minimum) - .20
square cm area
- 7mm:5ml volume (4ml minimum) - .38
square cm area
- 9mm:5ml volume (7ml minimum) - .64
square cm area
- 11.28mm:8ml volume (10ml minimum) - 1.00 square cm
area
- 15mm:12ml volume (11ml minimum) - 1.77 square cm
area
- 20mm:15ml volume (16ml minimum) - 3.14 square cm
area
- 25mm:20ml volume (25ml minimum) - 4.91 square cm
area
Standard unjacketed cells with clamp and stirbar
- 5mm:5ml volume (1ml minimum) - .20
square cm area
- 7mm:5ml volume (1ml minimum) - .38
square cm area
- 9mm:5ml volume (1.5ml minimum) - .64
square cm area
- 11.28mm:8ml volume (2ml minimum) - 1.00 square cm
area
- 15mm:12ml volume (5ml minimum) - 1.77 square cm
area
- 20mm:15ml volume (6ml minimum) - 3.14 square cm
area
- 25mm:20ml volume (10ml minimum) - 4.91 square cm
area
Call ++49 6736 1301 for current pricing. |
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Type 1 flow Franz cells are like static Franz
cells in that they have a sampling port as well as the flow ports. These
cells may be provided with female luer fittings and luer stoppers on the
ends of the flow ports so they can also be sampled through the sampling
arm and therefore used as static cells if desired.
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Type 2 flow Franz cells are just like Type 1
cells except that the manual sampling port is not present.
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Type
3 flow Franz cells have both flow ports coming out toward the user
from the front of the cell. Some researchers prefer this style of cell
because the receptor fluid is circulated through the entire volume of
the receptor compartment. Other researchers prefer the other types
because they believe that the flow needs only to be directly under the
membrane or device being studied to provide the necessary data.
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Type
4 flow Franz cells are essentially the same as Type 1 cells except
that the receptor input and output arms are made so the cells can be
placed adjacent to one another in a V6 or V9-C Stirrer when used as a
component in an automated system configuration.
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